Male
Multidisciplinary Team(s)
Thoracic Oncology
Department/Research Program(s)
Clinical Arrangements
Languages
English
Hindi
Marathi
Cancer Type(s)
Lung Cancer (Small Cell Non-Small Cell)
Mesothelioma
Esophageal Cancer
Contact Info
Email:
gadgeels@karmanos.org
Education
Fellowship
Hematology/oncology Fellowship: Wayne State University, Detroit, MI
Medical School
Grant Medical College, University of Bombay
Residency
Internal Medicine, Grant Medical College and J.J. Group of Hospitals, University of Bombay, Bombay, India
Residency
Internal Medicine Residency: Wayne State University, Detroit, MI
Graduate Training
Grant Medical College, University of Bombay
Professional Memberships/Associations
American Society of Clinical Oncology
International Association for the Study of Lung Cancer
Board Certifications
Medical Oncology
Hematology
American Board of Internal Medicine
Clinical Interests
Medical oncologist Multidisciplinary care of patients with lung cancer, mesothelioma and other chest cancers.
Research Interests
Clinical and Translational Research in Lung Cancer
Profile
Shirish M. Gadgeel, M.D., medical oncologist, leader of the Thoracic oncology Multidisciplinary Team at the Karmanos Cancer Center, President of the Medical Executive Committee of the Karmanos Cancer Center and associate professor of Hematology and oncology at Wayne State University School of Medicine, joined Karmanos in 2000. Dr. Gadgeel is also the medical director of the hematology/oncology inpatient unit. At Karmanos, Dr. Gadgeel is a member of various committees that review the scientific merit of proposed protocols to be conducted at Karmanos, and reviews and institutes various measures of quality of care for patients. He is also a member of the American Society of Clinical oncology and the Southwest oncology Group. His research focuses on conducting clinical and translational trials in the area of lung cancer and developmental therapeutics. Dr. Gadgeel's research interests have been funded by the National Cancer Institute, Southwest oncology Group, universities and pharmaceutical companies. He has won numerous awards including Wayne State University School of Medicine Teaching Award and the Merit Award from the American Society of Clinical Oncology. Dr. Gadgeel has authored more than 40 articles and seven book chapters, serves as reviewer for numerous journals, and sits on the editorial board of Clinical Lung Cancer. He received his M.D. in 1988 from Grant Medical College and J.J. Group of Hospitals at the University of Bombay in India. He completed a residency in internal medicine in India and an internship in internal medicine at LaGuardia Hospital in New York. Dr. Gadgeel completed a second residency in internal medicine and fellowship in hematology/oncology, both at Wayne State University School of Medicine. He also completed a fellowship in bone marrow transplantation at Wayne State University School of Medicine.
Awards
1997Merit Award, American Society of Clinical Oncology
1996Outstanding Fellow, Division of Hematology Oncology, Wayne State University, Detroit, MI
2012National Cancer Institute Cancer Clinical Investigator Team Leadership Award
Voted one of Best Doctors Inc. 2011-2012 Best Doctors of the Year
Publications
Up-regulation of sonic hedgehog contributes to TGF-B1-induced epithelial to mesenchymal transition in NSCLC cells. PLoS One 2011 Jan;6 (1):e16068. PMID 21249152. Authors: Maitah MY, Ali S, Ahmad A, Gadgeel S, Sarkar FH.
Frequency and Type of Epidermal Growth Factor Receptor Mutations in African Americans with Non-small Cell Lung Cancer. J Thorac oncol 2011 March;6:627-30. PMID 21317742. Authors: Cote ML, Haddad R, Edwards DJ, Atikukke G, Gadgeel S, Soubani AO, Lonardo F, Bepler G, Schwartz AG, Ethier SP.
Soy Isoflavones Augment Radiation Effect by Inhibiting APE1/Ref-1 DNA Repair Activity in Non-small Cell Lung Cancer. J Thorac oncol 2011 April;6:688-98. PMID 21325978. Authors: Singh-Gupta V, Joiner MC, Runyan L, Yunker CK, Sarkar FH, Miller S, Gadgeel SM, Konski AA, Hillman GG.
Phase II study of pemetrexed and cisplatin with chest radiotherapy followed by docetaxel in patients with stage III Non Small Cell Lung Cancer. J Thorac oncol 2011 May;6:927-33. PMID 21415776. Authors: Gadgeel SM, Ruckdeschel JC, Patel BB, Wozniak A, Konski A, Valdivieso M, Hackstock D, Chen W, Belzer K, Burger AM, Marquette L, Turrisi A.
Hope and Realism: The Perfect Balance? J Clin oncol 2011;29:2291-2. PMID 21383299. Author: Gadgeel SM.
